Displaying items by tag: xenotransplantation
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With news about UAB’s first peer-reviewed, published transplant of genetically modified pig kidneys into a brain-dead human individual, there are many questions about what this means for the future of transplant and how this will save countless lives moving forward.
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UAB physicians are working on the next steps to begin compassionate or emergency use of the pig kidneys in living humans. Two major approvals will be required.
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In the study published in the American Journal of Transplantation, UAB researchers tested the first human preclinical model for transplanting genetically modified pig kidneys into humans.
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Jim Parsons’ legacy paves the way for thousands to potentially receive lifesaving organs through UAB’s xenotransplantation program.
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The human preclinical model at UAB provides important knowledge before a Phase I clinical trial can begin for living human recipients. Decades of work by researchers across the world preceded UAB’s first clinical-grade pig kidney xenotransplant.
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From its incompatible kidney transplant program to deceased donor programs, to xenotransplantation, UAB continues to seek ways to help patients who face end-stage renal disease.
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Gift from United Therapeutics will establish Xenotransplantation Institute and bring additional resources to support the endeavor with a goal of genetically modified kidney transplants taking place by 2021.
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