Displaying items by tag: department of pathology

The Transfusion Medicine Service in the UAB Department of Pathology performs therapeutic apheresis on patients who have an illness associated with an abnormal cellular or plasma-based blood component.
Experts at UAB Hospital answer five common questions about blood donation.
The study’s findings suggest a combination therapy could be a more effective and a safer approach to treating metastatic colorectal cancer.
Goal of this UAB-led service is transforming the global landscape of TB research through accelerated study of human TB tissue.
American Red Cross will collaborate with UAB and Birmingham Barons to host two blood drives, as experts encourage the public to donate if able.    
By prohibiting the Activin A protein from functioning, researchers were able to halt the development of dyskinesia symptoms and effectively erase the brain’s “bad memory” response to L-DOPA treatments.
Use of high-speed video microscopy and artificial intelligence provides calculated statistics like diastolic and systolic diameters, fractional shortening, and ejection fraction.
A newly identified subset of intestinal epithelial cells act as both the major target and a key responder in a mouse model of gut infection by the bacteria Citrobacter rodentium.
These immune CD8 T cells may provide a target for treating the buildup of fatty lesions in the arteries called atherosclerosis.
Vascular stiffening and calcification, which is accelerated by aging, affects multiple organs and plays a role in dementia. There are no treatments for vascular calcification, which makes arteries harden.
This study, performed in a pre-clinical human model, is the first time xenotransplanted pig kidneys have shown clearance of creatinine and shown a standard immunosuppression regimen may be sufficient.
Some PD-1+CXCR5+CD4+ T cells will become germinal center-Tfh cells that are essential for B cells to become high-affinity antibody-producing cells. Others do not take that path, instead becoming memory T cells.
In a mouse model, border-associated macrophages, not microglia, were essential for the neuroinflammation that precedes neurodegradation. Targeting this subset could be a disease-modifying therapy in neurodegenerative disease.
This funding will be used to research multiple health conditions, including alcohol-related liver disease, Alzheimer’s disease, breast cancer, heart failure, inflammatory bowel disease and Zhu-Tokita-Takenouchi-Kim syndrome.
Suits for Success’ impact transcends to three other UAB closets and a community closet serving students, patients and underprivileged women facing domestic violence.
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