Associate Professor
Co-Director, Short-Term Research Experiences Advancing Medical Students (STREAMS)
Areas of Interest
trauma, hemorrhage, resuscitation, endothelial glycocalyx, lung injury, bioengineered in vitro models, mechanotransduction signaling
Biography
Dr. Jill Richter is an Associate Professor with Tenure of Surgery in the Division of Trauma & Acute Care Surgery at UAB. Dr. Richter is a biomedical engineer by training, and she received her B.S. and M.S. degrees from North Carolina State University. For her doctoral work, Dr. Richter attended the School of Biomedical Engineering and Sciences, a joint program between Wake Forest University and Virginia Tech, and she completed her research training at the Wake Forest Institute for Regenerative Medicine. Dr. Richter trained as an NIH T32 Postdoctoral Fellow at the University of Cincinnati in the Department of Surgery. After moving to UAB in 2013, Dr. Richter completed additional postdoctoral fellowships in the Departments of Radiology, Pathology and Anesthesiology. Her faculty appointment at UAB began in December of 2016 and in 2022 she became an Associate Professor with Tenure.
Selected Publications
Anand, T.; Crawford, A.E.; Sjoquist, M.; Hashmi, Z.G; Richter, R.P.; Joseph, B.A.; Richter, J.R. Decreased Glycocalyx Shedding on Presentation in Hemorrhaging Geriatric Trauma Patients. Journal of Surgical Research. 2024. 293, 709. PMID: 37844411.
*Pretorius, D.; *Richter, R.P.; Anand, T.; Cardenas, J.C.; Richter, J.R. Alterations in Heparan Sulfate Proteoglycan Synthesis and Sulfation and the Impact on Vascular Endothelial Function. Matrix Biology Plus. 2022. 16, 100121. PMID: 36160687. *co-first authors
Richter, R.P.; Ashtekar, A.R.; Pretorius, D.; Zheng, L.; Sanderson, R.D.; Gaggar, A.; Richter, J.R. Glycocalyx Heparan Sulfate Cleavage Promotes Endothelial Cell Angiopoietin-2 Expression by Impairing Shear Stress-Related AMPK/FoxO1 Signaling. JCI Insight. 2022. 7(15), e155010. PMID: 35763350.
Richter, R.P.; Joiner, D.M.; Griffin, R.L.; Jansen, J.O.; Kerby, J.D.; Wade, C.E.; Holcomb, J.B.; *Cardenas, J.C.; *Richter, J.R. Endotheliopathy is Associated with a Fibrinolysis Phenotype Described by Low TEG Lysis and High D-Dimer after Trauma: a Secondary Analysis of the PROPPR Study. Annals of Surgery Open. 2021. 3(1), e116. *co-senior authors
Walker, S.C.; Zheng, L.; Ashtekar, A.R.; Jansen, J.O.; Kerby, J.D.; Richter, J.R. Increased Plasma Hyaluronan Levels are Associated with Early Trauma-Induced Coagulopathy. Shock. 2021. 57(1), 113-117. PMID: 34608101.
*Uhlich, R.M.; *Richter, R.P.; Hu, P.; Kirkman, A.A.; Ashtekar, A.R.; Zheng, L.; Walker, S.C.; Reynolds, L.M.; Griffin, R.L.; Jansen, J.O.; Kerby J.D.; Richter, J.R. Temporal Dysregulation of Angiopoietins after Trauma and Associations with Injury Characteristics and Outcomes. Shock. 2020. 54(6):703. PMID: 32590696. *co-first authors
Richter, J.R.; Sutton, J.M.; Belizaire, R.M.; Friend, L.A.; Schuster, R.M.; Johannigman, T.A.; Miller, S.G.; Lentsch, A.B.; Pritts, T.A. 2014. Macrophage-Derived Chemokine (MDC/CCL22) is a Novel Mediator of Lung Inflammation Following Hemorrhage and Resuscitation. Shock. 42(6): 525.
Richter, J.R.; Mahoney, M.; Warram, J.M.; Samuel, S.L.; Zinn, K.R. 2014. A Dual-Reporter Diagnostic Vector for Detection and Localization of Prostate Cancer. Gene Therapy. 21: 897.
Burnett L.R.; Richter J.R.; Rahmany M.B.; Soler R.; Steen J.A.; Orlando G.; Aboushwareb T.; Van Dyke M.E. 2013. Novel Keratin (KeraStat™) and Polyurethane (Nanosan®-Sorb) Biomaterials are Hemostatic in a Porcine Lethal Extremity Hemorrhage Model. Journal of Biomaterial Applications, 28(6): 869.
Burnett, L.R.; Rahmany, M.B.; Richter, J.R.; Aboushwareb, T.A.; Eberli, D.; Ward, C.L.; Orlando, G.; Hantgan, R.; Van Dyke, M.E. 2013. Hemostatic Properties and the Role of Cell Receptor Recognition in Human Hair Keratin Protein Hydrogels. Biomaterials, 34(11): 2632.
Belizaire, R.M; Prakash, P.S.; Richter, J.R.; Robinson, B.R.; Edwards, M.J.; Caldwell, C.C.; Lentsch, A.B.; Pritts, T.A. 2012. Microparticles from Stored Red Blood Cells Activate Neutrophils and Cause Lung Injury after Hemorrhage and Resuscitation. Journal of American College of Surgeons, 214(4): 648.
Richter, J.R.; de Guzman, R.C.; Roberts, O.G.; Van Dyke, M.E. 2011. Structure-Function Relationship of Meta-Keratin Biomaterials Derived from Human Hair. Acta Biomaterialia, 8(1): 274.
Richter, J.R.; de Guzman, R.C.; Van Dyke, M.E. 2011. Mechanistic Investigation of Hepatocyte Attachment to Keratin Biomaterials. Biomaterials, 32(30): 7555.
Rouse, J.G. and Van Dyke, M.E. 2010. A Review of Keratin-Based Biomaterials for Biomedical Applications. Materials, 3(2): 999.
Rouse, J.G.; Haslauer, C.; Loboa, E.G.; Monteiro-Riviere, N.A. 2007. Cyclic Tensile Strain Increases Interactions between Human Epidermal Keratinocytes and Quantum Dot Nanoparticles. Toxicology In Vitro, 22(2): 491.
Rouse, J.G.; Yang, J.; Ryman-Rasmussen, J.P.; Barron, A.R.; Monteiro-Riviere, N.A. 2007. Effects of Mechanical Flexion on the Penetration of Fullerene Amino-Acid Derivatized Peptide Nanoparticles through Skin. Nano Letters, 7(1): 155.
Honors and Awards
2021 Pittman Scholar
Education
B.S. Biomedical Engineering
North Carolina State University
M.S. Biomedical Engineering
North Carolina State University
Ph.D. Biomedical Engineering
Wake Forest University
Contact
Campus Address
THT 1030
Phone
Patient Appointments and Questions: 205-975-7521
Academic Office: 205-975-7919