Associate Professor
Director, UAB Pancreatobiliary Disease Center
Chief, Section of Hepatopancreatobiliary Disease

Areas of Interest
diseases of the stomach, small bowel, liver, pancreas, gallbladder, and bile duct, Notch signaling pathways in gastroenteropancreatic neuroendocrine tumors

Biography

Dr. J. Bart Rose joined the faculty of the UAB Department of Surgery Division of Surgical Oncology in 2017. He has a combined research and clinical appointment. He has been engaged in scientific research over 20 years. Over this time he contributed to scientific knowledge in the fields of molecular genetics, enzymology, oncologic biomarkers, and clinical outcomes. His focus since entering the field of surgery has been on biomarker research and mechanisms of cancer development in liver, pancreas, and bile ducts cancers (specifically neuroendocrine tumors). He has presented on novel uses of established biomarkers in pancreatic cancer, was the first to report on the clinical utility of a bile based biomarker in patients with bile duct cancer (cholangiocarcinoma), and is currently investigating new ways to treat tumors of the pancreas and GI tract.

He is originally from a small logging town in Northern California, but has enjoyed his time during training in the Midwest and Pacific Northwest. He loves living in Alabama with his wife and three daughters. His hobbies include working on classic cars, coaching softball, and home improvement.

Education

Graduate School
University of California, San Diego
Masters in Leadership of Healthcare Organizations

Medical School
University of Illinois College of Medicine

Residency
Virginia Mason Medical Center, Seattle, Washington
General Surgery

Fellowship
Washington University, St. Louis, Missouri
Hepatopancreatobiliary Surgery

Certification

American Board of Surgery (2016)

Selected Publications

Guenter R, Zheng-Pywell R, Herring B, Murphy M, Foote J, Benner K, Rose JB. Preclinical safety evaluation of continuous UV-A lighting in an operative setting. PLoS One. 2023;18(11):e0291083.

Herring B, Bonner A, Guenter R, Vickers S, Yates C, Lee G, Dhall D, Chen H, Rose JB. Representation of Racial Groups in Genomic Studies of Gastroenteropancreatic Neuroendocrine Neoplasms. Cancer Res Comm. 2022 Sep 9; 2 (10), 1162-1173.

Zheng-Pywell R, Lopez-Aguiar A, Fields R, Vickers S, Yates C, Dudeja V, Chen H, Reddy S, Maithel SK, Rose JB. Are we undertreating Black patients with nonfunctional pancreatic neuroendocrine tumors? A critical analysis of current surveillance guidelines by race. J Am Coll Surg. 2022 Apr: 234(4):599-606

Rose JB, Correa-Gallego C, Nelson J, Alseidi A, Helton S, Allen PJ, D'Angelica M, DeMatteo RP, Fong Y, Kingham PT, Kowdley K, Jarnagin WR, Rocha FG. Role of biliary CEACAM6 as a biomarker for cholangiocarcinoma. PLoS One. 2016 Mar;11(3):e0150195

Rose JB, Rocha FG, Alseidi A, Biehl T, Moonka R, Ryan JA, Lin B, Picozzi V, Helton S. Extended neoadjuvant chemotherapy for borderline resectable pancreatic cancer demonstrates promising postoperative outcomes and survival. Ann Surg Oncol. 2014 May;21(5):1530-7

Rose JB, Bilderback P, Raphaeli T, Traverso W, Helton WS, Ryan J, Biehl T. Use The Duodenum, It’s Right There: A retrospective cohort study comparing biliary repair utilizing either the jejunum or duodenum. JAMA Surgery. 2013 Sep;148(9):860-5

Rose JB, Rockenstein E, Adame A, Mante M, Crews L, Hersch L, Gage F, Marr R, Masliah E. Neuropeptide Y fragments derived from neprilysin processing are neuroprotective in a transgenic model of Alzheimer's disease. J Neurosci. 2009 Jan 28;29(4):1115-25 - Reported in Nature Medicine. 2009 Mar;15(3):256.

Contact

Campus Address
BDB 583

Phone
205-934-3028

Email
jbrose@uabmc.edu