UAB is one of over 600 institutions that have joined SMART IRB. SMART IRB stands for "Streamlined, Multisite, Accelerated Resources for Trials". SMART IRB is an IRB reliance model designed to streamline the IRB review process for multi-site studies, while ensuring a high level of protection for research participants. SMART IRB can be used for a range from large, complex clinical trials to two-site collaborations.
As part of SMART IRB, institutions may choose to rely on another IRB or have their IRB act as the Reviewing IRB with other institutions relying on it. The Reviewing IRB takes on IRB oversight responsibilities associated with that study throughout its duration. Relying Institutions provide key local context information about state law, study team member training and qualifications, and any applicable conflict of interests. Investigators and institutions retain their respective responsibilities for the protection of human subjects, compliance with applicable laws, regulations, ethical standards, and the terms of institution's FWA.
UAB Single IRB Team