The Wesselmann Lab is led by Ursula Wesselmann, M.D., Ph.D.
To contact Dr. Wesselmann, email ursulawesselmann@uabmc.edu
To donate to Dr. Wesselmann's research, click here.
This fund supports her work in the Pain and Quality of Life in Breast Cancer Survivors Research Program and Pelvic and Urogenital Pain in Women Research Program.
Dr. Wesselmann has a long-standing interest in the neurobiological mechanisms of chronic pain syndromes in women. She holds the William A. Lell, M.D.,-Paul N. Samuelson, M.D., Endowed Professorship in Anesthesiology. She is a clinical neurologist and experimental neuro-physiologist with sub-specialty training in pain management. Over the last 20 years NIH-funded studies in her translational research laboratory have focused on the common theme of (1) elucidating peripheral and central pain mechanisms via neurophysiological, neuroanatomical and psychophysical paradigms in health and disease, specifically in females and (2) phenotyping subgroups of patients with pain syndromes based on different pathophysiological mechanisms, with the goal of identifying novel treatment strategies for these different phenotypes based on the underlying pathophysiology. Her current research, in collaboration with Dr. P. Czakanski (Depts. of Anesthesiology and Obstetrics & Gynecology), focuses on neurophysiological, psychosocial and autonomic factors that contribute to the onset and maintenance of chronic urological (interstitial cystitis) and gynecological (vulvodynia) pain syndromes in women. A new area of research investigation is to determine the biological, psychological, and socio-cultural variables contributing to pain and pain-related disability in women treated for breast cancer. The long-term goal of her research program is to translate new discoveries into clinical practices that improve the ability to diagnose and treat women experiencing chronic pain.
To learn more about Dr. Wesselmann, read her bio.
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Recent Publications
For a full list of publications prior to 2022, see her NIH Bibliography.
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Edwards RR, Schreiber KL, Dworkin RH, Turk DC, Baron R, Freeman R, Jensen TS, Latremoliere A, Markman JD, Rice ASC, Rowbotham M, Staud R, Tate S, Woolf CJ, Andrews NA, Carr DB, Colloca L, Cosma-Roman D, Cowan P, Diatchenko L, Farrar J, Gewandter JS, Gilron I, Kerns RD, Marchand S, Niebler G, Patel KV, Simon LS, Tockarshewsky T, Vanhove GF, Vardeh D, Walco GA, Wasan AD, Wesselmann U. Optimizing and Accelerating the Development of Precision Pain Treatments for Chronic Pain: IMMPACT Review and Recommendations. J Pain. 2023 Feb;24(2):204-225. doi: 10.1016/j.jpain.2022.08.010. Epub 2022 Oct 2. Review. PubMed PMID: 36198371.
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Sun Y, Zabihi M, Li Q, Li X, Kim BJ, Ubogu EE, Raja SN, Wesselmann U, Zhao C. Drug Permeability: From the Blood-Brain Barrier to the Peripheral Nerve Barriers. Advanced Therapeutics. 2023 January; 202200150. doi: https://doi.org/10.1002/adtp.202200150.
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Li X, Li Q, Song S, Stevens AO, Broemmel Z, He Y, Wesselmann U, Yaksh T, Zhao C. Emulsion-Induced Polymersomes Taming Tetrodotoxin for Prolonged Duration Local Anesthesia. Advanced Therapeutics. 2022 October; 2200199. doi: https://doi.org/10.1002/adtp.202200199.
- Hanno PM, Burks DA, Clemens JQ, Dmochowski RR, Erickson D, Fitzgerald MP, Forrest JB, Gordon B, Gray M, Mayer RD, Moldwin R, Newman DK, Nyberg Jr. L, Payne CK, Wesselmann U, Faraday MM, Varela N, Lai HH. Diagnosis and Treatment of Interstitial Cystitis/Bladder Pain Syndrome [Unabridged version - PDF]. [Internet]. Linthicum, MD: American Urological Association, Guidelines; 2022 May. Available from: https://www.auanet.org/guidelines-and-quality/guidelines/diagnosis-and-treatment-interstitial-cystitis/bladder-pain-syndrome-(2022)
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Active Grants and Other Support