The PRMC reviews all cancer-related projects at UAB. The investigator first presents the project to one of the 15 Disease Specific Working Groups. Once the project is approved by the Working Group, a Clinical Research Administrator with provide the PI with a RedCap PRMC submission form.
If a full review is required by the PRMC (e.g., an interventional treatment trial), the PRMC provides review for scientific merit, safety, study design, and feasibility. In addition, each trial is reviewed to ensure that no competing studies would prevent the trial from reaching its targeted accrual goal. After review, the trial is assigned a priority score based on clinical and scientific merit. The PRMC review may serve as the Protocol Oversight Review for some divisions/departments. Researchers should check with their departments to see if departmental review is also required. The IRB submission materials should include a copy of the PRMC approval memorandum, and a copy of the departmental review form if required.
Where a full review is not required by the PRMC (e.g., retrospective chart review studies, coordinating center and administrative protocols), either a limited review or an approval memorandum is provided following expedited review. The IRB submission materials should include a copy of the PRMC approval memorandum, and a copy of the departmental review form if required.
Questions regarding the PRMC review process should be directed to