The Targeted Exercise for African Americans with Multiple Sclerosis (TEAAMS) study will examine whether a 16-week home-based, racially-tailored exercise training program can provide improvements in walking dysfunction, symptoms, and quality of life among Black/African Americans with MS who live in rural communities in the Southeastern US. Eligible participants must be 18-64 years old, diagnosed with MS, self-identify as Black or African American, and live in the Southeastern US. Participants will be compensated $90 for completing all study visits. Please contact Edson Flores at enrl@uic.edu or (833) 727-1887 for more information and to see if you qualify.

Adult ages 40-80 are needed for a study about the anti-inflammatory effects of ensifentrine in patients with COPD. The study involves 7 visits in our clinical research unit, and the collection of urine and blood. Compensation up to $700. For more information, call 205-996-2727 or email Carrie at LungHealth@uabmc.edu.

Help us find out by joining our study. The University of Alabama at Birmingham, Department of Nutrition Sciences, is conducting an exciting research study, in collaboration with Pennington Biomedical Research Center, to investigate whether intermittent fasting or calorie restriction (i.e., losing weight) can improve health and slow the aging process.

If you are randomly selected to do calorie restriction, you may lose weight by eating less. If you are randomly selected to do intermittent fasting, you will fast for 16 hours per day and eat dinner by 6 pm about 6 days per week (1 break day per week). We want you to be successful: the study provides intensive coaching and support to help you successfully lose weight or practice intermittent fasting.

To qualify, you should:

Be 25-45 years old
Have a BMI between 22-30 Calculate your BMI here
Be healthy
Not currently taking any medications or supplements for chronic conditions
Not smoke, vape, or use tobacco products currently or within the last 6 months
Not currently participate in a regular program of heavy physical activity (e.g., jogging, running, or riding fast on a bicycle for 30 minutes or more per day)
The study involves collecting a medical history, body fat and bone scans, blood draws, urine collection, questionnaires, and other simple tests. Participation in the study will last approximately 7 months. Compensation of up to $1,500 is offered for the completion of this study. If you are interested in participating and think you may be eligible, please click the button below to screen online, call 205-934-1457, or email dial@uab.edu.

You may be eligible to participate in a research study looking at the effects of sacubitril/valsartan on how your body handles insulin and glucose. This medication is related to blood pressure. Eligible participants must be healthy men and women, African American, and have no history of diabetes, heart problems, or kidney problems. The study involves performing some exercise, taking sacubitril/valsartan, and collecting blood samples. Participants will be compensated $675 for completing all the visits. To participate, please contact Haley at 205-975-5825 or email us at nauticalstudy@uabmc.edu.

Beginning Oct. 5, the righ-thand turn lane from eastbound University Boulevard onto 18th Street South will be closed until further notice as renovations begin in Unity Park. The southern travel lane may also experience occasional, temporary closures during construction work periods; right-hand turns onto 18th will remain possible.

Adult Volunteers ages 18-75 are needed for a study examining the relationship between oxalate handling in the blood and urine in persons with and without chronic kidney disease. The study involves consuming prepared meals over 5 days twice, one-day long visit in our clinical research unit, and the collection of urine and blood. Compensation up to $360. For more information, call 205-224-7324 or email kidneystoneresearch@uabmc.edu.

Healthy individuals ages 18-75 are needed for a study examining the relationship between oxalate handling in the blood and urine in persons with and without chronic kidney disease. The study involves consuming prepared meals over 5 days twice, one-day long visit in our clinical research unit, and the collection of urine and blood. Compensation up to $360. For more information, call 205-224-7324 or email kidneystoneresearch@uabmc.edu.

Do you have a loved one with agitation associated with Alzheimer’s dementia? Is their agitation becoming overwhelming? Examples of some easily identifiable agitated behaviors are: restlessness, screaming, shouting, throwing things, resistiveness, constant unwarranted requests for attention or help, pacing/aimless wandering, kicking, hitting others or self, pushing people, hurting self or others, tearing things or destroying property. In this study, researchers want to find out if an investigational drug called AVP-786 is safe and effective (useful) in managing agitation in adults with Alzheimer’s dementia, when compared to a placebo. If you are a caregiver for a person with Alzheimer’s disease, please call (205) 996-5987 or email lalexander@uabmc.edu for more information.

If you’re being treated for MDD and your current antidepressant medication(s) is not working, the SAVITRI Study might interest you. The SAVITRI Study is researching a potential MDD therapy to improve symptoms of depression, and you may be able to participate. This research study is now enrolling adults diagnosed with MDD. Those who qualify will receive the investigational medication (or placebo), study-specific medical exams, and study-specific laboratory tests at no cost. Participants in the SAVITRI Study must: be 18 to 65 years of age; have a clinical diagnosis of MDD; be currently on antidepressant medication(s); have had inadequate response to up to 5 oral antidepressant medications; and fulfill other eligibility criteria. For more information, please call (205) 996-5987 or email lalexander@uabmc.edu. Please mention SAVITRI in your message.

Help us find out by joining our study at UAB You may be eligible to participate in the PRECISION-BP research study about the effects of Sacubitril/Valsartan or Valsartan on your body’s 24-hour rhythm of a hormone in your blood called natriuretic peptides. This hormone and the study medications are related to the heart. Eligible participants must be obese (BMI: 30-45 kg/m2) men and women, have high blood pressure, and have no history of heart or kidney problems. The study involves wearing a blood pressure monitor for 24 hours, 24-hour inpatient visits at UAB hospital, taking medications, and collecting blood and urine samples. Meals will be provided at no cost. Participants will be compensated $575 for completing the study visits. Please e-mail Nehal at PRECISION-BPSTUDY@uabmc.edu or call us at 205-934-7173 if you are interested