If you’re being treated for MDD and your current antidepressant medication(s) is not working, the SAVITRI Study might interest you. The SAVITRI Study is researching a potential MDD therapy to improve symptoms of depression, and you may be able to participate. This research study is now enrolling adults diagnosed with MDD. Those who qualify will receive the investigational medication (or placebo), study-specific medical exams, and study-specific laboratory tests at no cost. Participants in the SAVITRI Study must: be 18 to 65 years of age; have a clinical diagnosis of MDD; be currently on antidepressant medication(s); have had inadequate response to up to 5 oral antidepressant medications; and fulfill other eligibility criteria. For more information, please call (205) 996-5987 or email lalexander@uabmc.edu. Please mention SAVITRI in your message.

Help us find out by joining our study at UAB You may be eligible to participate in the PRECISION-BP research study about the effects of Sacubitril/Valsartan or Valsartan on your body’s 24-hour rhythm of a hormone in your blood called natriuretic peptides. This hormone and the study medications are related to the heart. Eligible participants must be obese (BMI: 30-45 kg/m2) men and women, have high blood pressure, and have no history of heart or kidney problems. The study involves wearing a blood pressure monitor for 24 hours, 24-hour inpatient visits at UAB hospital, taking medications, and collecting blood and urine samples. Meals will be provided at no cost. Participants will be compensated $575 for completing the study visits. Please e-mail Nehal at PRECISION-BPSTUDY@uabmc.edu or call us at 205-934-7173 if you are interested

The Kids Low Vision and Reading (KLoVR) study aims to better understand reading ability among children with permanent vision impairment. We need to recruit children ages 6 to 16 with normal vision (glasses are ok) for a comparison group. Testing includes vision testing, reading tests and memory tests and lasts 2 to 2.5 hours. No eyedrops are used. Participants are compensated with a $100 gift card and free parking in the Callahan Eye Hospital parking deck. Please call the Clinical Research Coordinator, Caroline Durena, in the Center for Low Vision and Rehabilitation at (205)488-0788 for more infor‐ mation about the study and to see if you qualify. This study is funded by the National Institute for Disability, Independent Living and Rehabilitation Research.

If you are currently pregnant, 18 or older, planning to deliver at UAB, and planning to breast feed, you may be eligible for our study. This study focuses on better understanding CMV, a common virus most people in the US are infected with by adulthood, its transmission through breast milk from mother to baby, and how the body protects itself from the virus. Participants will meet with study staff once a month for six months to collect non-invasive samples and answer a questionnaire. Samples collected include oral swabs from you and your baby, a small quantity of breast milk and a skin swab from you, and a urine and stool sample from your baby. Participants will be compensated up to $300 for completing the study visits and providing samples. Eligible participants may also qualify for additional sub-studies for additional compensation up to $800. For more information, please contact Amanda Rafferty at 205-975-3752 or email amrafferty@uabmc.edu.

We are looking for current pessary users to trial a new investigational pessary, which may be more comfortable and easier to use than your current pessary. Participants will be asked to: Continue to wear your current pessary for 1 month Be willing to use a study pessary for 3 months Attend 1-2 visits (at no cost to you) in addition to your pessary usual care Participants will receive: $300 ($100 gift card given for each extra visit and then at the end of the study) For more information call 205-934-5498

Participate in nationwide study to understand why some people have prolonged symptoms (referred to as long COVID or post-acute sequelae of SARS-CoV-2, also called PASC) or develop new or returning symptoms after the acute phase of SARS-CoV-2 infection. We need COVID-19 survivors from the Birmingham and Mobile, Alabama, and New Orleans, Louisiana, areas. If you are over 18 years old, not pregnant, and would like to take part in UAB’s study, email COVIDResearch@uabmc.edu to find out more.

Obese adults, age 25 to 45 years old, are needed to determine if the timing of salt intake affects blood pressure throughout the day. This study involves 12 visits over 8 weeks. Participants will be compensated for participation. You may not be eligible to participate if you have significant health problems, are pregnant, or are taking certain medications. Please contact Alexis at aelambert@uabmc.edu or call (205) 582-7761 if you are interested in learning more about this study.

The University of Alabama at Birmingham, Department of Nutrition Sciences, in collaboration with Novo Nordisk, is conducting a 52 week research study to look into how well semaglutide once weekly medicine works at different doses in people with type 2 diabetes and overweight Qualified participants will receive study drug free of charge and may be compensated for time and travel. For more information, and to see if you might be eligible to join, please contact (205) 996-4015 or email at ccnrn@uab.edu.

Are you a Female and Experience a Loss of Urine with Urge and Frequency? Do you have Overactive Bladder with Urinary Leakage? To find out if you are eligible, please call at 205-934-1777 or email Dr. Russell Stanley at russellstanley@uabmc.edu. $200 Compensation will be provided.

Do you have infrequent or irregular cycles? or Do you have excessive hair growth on your upper lip, chin, chest, abdomen, buttocks, or back? If you are between 18 and 35 years old, and answered YES to any of the questions above you may qualify for this study. Benefits: Free physical exam, labs and ovarian imaging, Receive up to $600 for complete participation in the study. Help to improve our understanding of women's health. For More information Please call (205) 934-0877 or email slangan@uabmc.edu