Research - News
Results from the Chronic Hypertension and Pregnancy trial found treating preexisting mild chronic hypertension in pregnant women is safe from both the mom and baby. Results published in April 2022 have since led to changes in national guidelines.
The University of Alabama at Birmingham has been awarded $8 million from the United States Department of Energy’s National Nuclear Security Agency.
New study indicates that StreetBit has the potential to save millions of dollars annually and reduce pedestrian injuries by implementing such programs on a larger scale.
UAB was one of four sites leading a clinical trial to evaluate the effectiveness of adding Pembrolizumab to endometrial cancer care.
Knowledge of this previously unrecognized mechanism may aid therapy for patients with interleukin-6 signaling mutations and hyper-IgE Syndrome, or HIES.
Uncovering a pathophysiological mechanism that initiates, transitions and sustains neuropathic pain holds promise for treating neuropathic pain.
Description of this mechanism offers a promising therapeutic target to limit lung injury and death. Lower respiratory tract infections, including bacterial pneumonia, are the fourth-leading cause of death worldwide, with 120 million to 156 million cases and 1.4 million deaths a year.
This study will examine the average treatment effects of M2M-C, a telehealth cardio-focused exercise program, on core indicators of major cardiometabolic risk factors.
Three teams of researchers from UAB are analyzing the intergenerational transmission of obesity.
This is the first example of a chelator-free-radiolabeled polymersome capable of a long-term multiday positron emission tomography, or PET, imaging study in vivo.
The drug appears to help strengthen pathways in the brain, improving the ability of neurons to communicate with each other.
Advanced warning of an elevated risk for seizures could help patients take protective measures to minimize the effects, or possibly even stop the seizure before it begins.
The Alabama Innovation Corporation awarded two UAB startups with grants during the second round of Innovate Alabama Supplemental Grant awards.
Researchers identify a new target to fight infections caused by the opportunistic lung pathogen Streptococcus pneumoniae — interference with the bacteria’s fermentation metabolism.
The study found that using a vaginal swab was more accurate than using urine for three types of sexually transmitted infections.
These effector memory B cells appear poised for a rapid serum antibody response upon secondary challenge one year later, and evidence shows that the cells in this subset differ from all previously described memory B cell subsets.
The trial will evaluate the effects of low doses of psilocybin on combating demoralization in broader populations.
The All of Us Southern Network has enrolled more than 30,000 people. The new Dothan location will extend enrollment opportunities into the Wiregrass.
The grant validates the science of Alveolus Bio, and the funds will support development of first-of-its-kind inhaled biotherapeutics to treat chronic lung diseases.
The federal mandate, which was announced in 2011 and implemented in 2014, limited acetaminophen to 325 milligrams per opioid-acetaminophen combination pill. Acetaminophen is toxic to livers at high doses.

The National Endowment for the Arts has awarded UAB Arts in Medicine a research grant to study whether magic arts training can help improve motor and social-emotional function.

Neuroengineering blends engineering principles with neuroscience to find better ways to treat neurological conditions and to build on understanding how the brain and nervous system function.
The findings indicate that inflammation is present in the brain early in the disease’s progression, but how inflammation affects disease progression remains unknown.
Having a bacterial infection at the same time as COVID-19 is a greater risk factor for COVID-19 severity and mortality than previously described risk factors such as advanced age, male sex or various comorbidities.
Published results show that higher cardiorespiratory fitness in early adulthood produces a lower risk of all-cause mortality later in life. Additionally, retaining good cardiorespiratory fitness through midlife reduces the later risk of death.
Whistleblowers in marketing channels can be useful in encouraging an efficient supply chain, which can lower production costs and slow down inflation.
Research funding to UAB from the National Institutes of Health tops $300 million again.
The UAB-led consortium, begun in 2006, has expanded to 24 clinical sites and conducted 18 clinical trials.
The clinical trial focused on very young children, who have a more rapid loss of the pancreatic beta cells than do adolescents. The trial was constrained to a low-dose level, but showed safety and tolerability and reduced serum glucagon, a secondary outcome.
The research team analyzed the clinical outcomes of more than 12,000 patients who had a TEE-guided percutaneous transcatheter intervention and found that, over the past decade, 3.6 percent of patients who had this procedure had complications.
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