ICOS ligand and IL-10 synergize to promote host–microbiota mutualism
Written by Mary Ashley Canevaro
Craig Maynard, Ph.D., assistant professor in the Department of Pathology, is the latest winner of the School of Medicine’s Featured Discovery. This initiative celebrates important research from School of Medicine faculty members.
Maynard and his team were recently published in PNAS for their study “ICOS ligand and IL-10 synergize to promote host–microbiota mutualism.”
In the study, Maynard and his team, including first author Ashley Landuyt, Ph.D., former student in the Immunology Theme of the Graduate Biomedical Science (GBS) program, compared normal mice with mice devoid of the T cell co-stimulatory protein ICOSL, to help determine the role of this protein in the regulation of immune responses in the intestine.
Siegal Elected Vice-President of International Society of Bone and Soft Tissue Pathology
Gene Siegal, M.D., Ph.D., UAB Distinguished Professor, Robert W. Mowry Endowed Professor and Executive Vice Chair, Department of Pathology, has been elected vice president of the International Society of Bone and Soft Tissue Pathology. He will automatically ascend to the presidency of the organization in two years.
In April 2021, Siegal was appointed Distinguished Professor by the University of Alabama Board of Trustees, the first such honor for a pathologist at UAB.
“I am highly moved that my colleagues around the world have honored me in this way with this opportunity to further serve them at this time in my life," Siegal said.
Read moreVarambally Recognized by Society of American Asian Scientists in Cancer Research
Sooryanarayana Varambally, Ph.D., Professor, Molecular & Cellular Pathology, was presented with the Outstanding Achievement Award by the Society of American Asian Scientists in Cancer Research (SAASCR) at this year's American Association for Cancer Research (AACR) annual meeting, held virtually in May 17-21.
Varambally is Director of Integrative Translational Oncologic Pathology research and Co-director of the Graduate Biomedical Sciences program in Cancer Biology, and a scientist with the O'Neal Comprehensive Cancer Center, the Informatics Institute, and the Center for Clinical and Translational Science. The award recognizes, "his seminal contributions to the field of cancer research."
The Society of American Asian Scientists in Cancer Research is a nonprofit organization of more than 5,000 scientists from Asia who are working in the U.S. and Canada in the field of cancer research.
Read moreDiversity Dialogue: Dr. Rajeev Samant
Rajeev Samant, Ph.D., is a Professor in the division of Molecular and Cellular Pathology, and a member of the Department of Pathology's Diversity Task Force. This group meets regularly and includes representatives from around the department, including faculty, staff, and trainees. Here, Dr. Samant answers some questions about his experiences with diversity.
Read morePathology Celebrates Four SOM Dean's Excellence Award Winners in 2021
The Dean's Excellence Awards are annual honors awarded to select UAB School of Medicine faculty for excellence in the areas of teaching, service, research, mentorship, and diversity enhancement. Awardees are chosen through a peer-review process and facilitated by a member of the dean's leadership team.
In 2021 the school recognized 18 faculty for their outstanding achievements, and the UAB Department of Pathology is excited to have four winners this year: Peter Anderson, DVM, Ph.D., Professor, Molecular & Cellular Pathology, senior award for teaching; Brandi McCleskey, M.D., Assistant Professor, Forensic Pathology, junior award for mentoring; Sixto Leal, Jr., M.D., Ph.D., Assistant Professor, Laboratory Medicine, junior award for service; and Frida Rosenblum Donath, M.D., Assistant Professor, Anatomic Pathology, junior award for teaching.
Peter Anderson, D.V.M., Ph.D., is the 2021 recipient of the Dean’s Excellence Award in Teaching for senior faculty. Anderson is a professor in the Department of Pathology, Division of Molecular and Cellular Pathology and the Director of Pathology Undergraduate Education at the UAB School of Medicine.
Read moreMahler Receives 2021 William Boyd Medal in Pathology
UAB medical student Lily Mahler is the 2021 recipient of the William Boyd Medal at the 2021 University of Alabama School of Medicine Dean's Awards ceremony, held virtually on May 20, 2021. The Boyd Medal is given each year to the UAB medical student whose performance in all aspects of their pathology education has been most outstanding.
Mahler attended Auburn University for her undergraduate studies in microbiology and graduated from the University of Alabama School of Medicine with her medical degree in May. She served as a Medical Student Research Assistant in 2020 under Brandi McCleskey, M.D., Assistant Professor, Division of Forensic Pathology, where she participated in research efforts with the UAB School of Medicine (SOM) and the Jefferson County Medical Examiners Office. In this role, Mahler learned literature review and manscript drafting. She gained additional research experience in 2018 from the laboratory of John Hartman, I.V., M.D., Assistant Professor, Department of Genetics, where she studied NF1 gene regulation via phenomic characterization of Saccharomyces cerevisiae homolog IRA2. Mahler will move to Boston to work as a pathology resident at Beth Israel Deaconess Medical Center.
Read moreSiegal Named UAB Distinguished Professor
In his fourth decade of service to UAB, Gene Siegal, M.D., Ph.D., Robert W. Mowry Endowed Professor and Executive Vice Chair, Department of Pathology, can add the title of Distinguished Professor to his long list of accomplishments. Siegal’s appointment was approved by the University of Alabama Board of Trustees in April 2021, and is the first such honor for a pathologist at UAB.
During his 30+ year tenure at UAB, Siegal has set a high standard through his professional, academic, research, and service contributions. In his current role as Executive Vice Chair, he delivers tremendous administrative support and experience to the operations of both the department and the institution.
“By the very nature of his more than three-decade commitment to excellence in this academic community, his unwavering dedication to groups underrepresented in medicine, and the recognition and goodwill he has generated for UAB by the model of physician-scholar that he sets, Dr. Siegal is worthy of being named a Distinguished Professor,” says George Netto, M.D., Robert and Ruth Anderson Endowed Chair, UAB Department of Pathology. “We are very proud to see him recognized by the institution for his lifelong commitment to clinical, educational and administrative endeavors.”
Read moreFrom Trainee to Faculty
In the Department of Pathology, we are fortunate to have several faculty members who worked as trainees at UAB at one point or another in their academic careers. Follow along with a few of them as they describe when they first came to UAB, and how they wound up as full-time faculty on our team. Their stories are varied, and we are thrilled to count them all as colleagues.
Read more
New UAB lab expands genomic diagnostic testing
Media contact: Bob Shepard
University of Alabama at Birmingham School of Medicine and UAB Hospital laboratories have established the Genomic Diagnostics Lab, a first step toward an expanded offering of genomic diagnostic testing at UAB. This collaborative project with the UAB Department of Pathology’s Genomic Diagnostics and Bioinformatics Division and UAB Hospital opened in January 2021.
The Read moreUAB Pathology Celebrates Medical Lab Professionals Week
This year April 18-24 is Medical Laboratory Professionals Week, an annual celebration of medical laboratory professionals and pathologists who play a vital role in health care and patient advocacy led by the American Society for Clinical Pathology. Celebrations took place throughout the week, including lunches for lab staff on Wednesday, April 21, and a photo contest. The Lab Week Photo Contest, sponsored by Marisa Marques, M.D., Interim Division Director, Laboratory Medicine, asked department and hospital lab staff to submit images that "identify beauty found in the midst of a global pandemic."
First Place Winner:
New Year, New Tools
Better Genomic Diagnostics for AlabamaBy Christina Crowe Alexander “Craig” Mackinnon, M.D., Ph.D., division director, Genomic Diagnostics and Bioinformatics has anything to say about it. Last year we brought you the story of how Mackinnon joined the Department of Pathology and under the leadership of George Netto, M.D., Robert and Ruth Anderson Endowed Chair, outlined several initiatives for 2020, including the creation of a precision diagnostics laboratory. That plan was part of Netto’s vision for the department when he came to serve as chair four years ago. Genomic diagnostics are poised to play an increased role in precision medicine at UAB and throughout the state, if Read moreUAB Pathology Celebrates Pathologists' Assistants Day
By: Christina Crowe
Published Date: Apr 14
This year, April 14, is Pathologists’ Assistants (PA) Day, a day of appreciation led by the American Association of Pathologists’ Assistants. Raima Memon, M.D., PGY3 Chief Resident, Anatomic Pathology, wrote the following to describe the important role of a PA in pathology, and to celebrate our department’s three hardworking PAs, Joe Begany, Audrey Alexander and Kaitlin Forsythe.
What role does the PA play in the pathology “process”? PAs are an integral part of the UAB Pathology team. They perform many tasks including, but certainly not limited to: Grossing surgical specimens, procurement research specimens, and training pathology residents. What role do they play in our Department in particular? Our PAs have re-shaped the surgical pathology experience. They facilitate resident education not only by teaching and supervising residents during grossing, but also by allowing time to focus on complex and educational specimens. The PAs have been integral in updating equipment (bone saw), safety measures (cut-resistant gloves) and improving specimen turnaround time (increased processing for fatty specimens and submitting additional sections). Read moreDiversity Dialogue: Dr. Adam Wende
By: Christina Crowe
Published Date: Mar 30
Adam Wende, Ph.D., is an Associate Professor, Molecular & Cellular Pathology, and a member of the Department of Pathology's Diversity Task Force. This group meets regularly and includes representatives from around the department, including faculty, staff, and trainees. Here, Dr. Wende answers some questions about his experiences with diversity.
Near the southside of Chicago, in Hometown and Oak Lawn, IL, but I also have influences from living 4 years in rural Galesburg, IL; 6 years in St. Louis, MO; and 7 years in Salt Lake City, UT. Read moreDiversity Dialogue: Dr. Xu Feng
By: Christina Crowe
Published Date: Mar 30
Xu Feng, Ph.D., is a Professor in the division of Molecular and Cellular Pathology, and a member of the Department of Pathology's Diversity Task Force. This group meets regularly and includes representatives from around the department, including faculty, staff, and trainees. Here, Dr. Feng answers some questions about his experiences with diversity. Read moreUAB Pathology Welcomes 2021-22 Residents on Match Day
By: Christina Crowe
Published Date: Mar 20
We are excited to announce the successful completion of this year’s residency match program where filled all six of our open slots for 2021-22. Please join us in welcoming the following individuals to our team: Read moreBaker Family Expands Former Chair’s Legacy with Donation to UAB Pathology
By: Christina Crowe
Published Date: Mar 19
Roger Denio Baker, M.D. (1902–1994) (Denio rhymes with Ohio) was the founding chair of the UAB Department of Pathology from 1944 to 1952. Twenty-one years ago, Baker’s family established the Roger Denio Baker Endowed Support Fund in Anatomical Pathology in his honor. Each year, an award is made from that fund to the resident or fellow who exhibits the greatest skill in the disciplines of Anatomic Pathology. This spring a substantial contribution from the Baker family has insured that the Baker prizes can continue to be awarded annually in perpetuity. “The UAB Department of Pathology is grateful for the ongoing support of the Baker family for our programs, and in particular our trainees,” said George Netto, M.D., Robert and Ruth Anderson Endowed Chair. “We have a long history of dedication to our education programs and the training of future pathologists. This support is vital to enhancing these training programs.” The Baker Prize was first awarded in 2002 and, until 2019, was presented annually, at a year-end reception honoring trainees, by David Remember Baker, Dr. Baker’s eldest son. Mr. Baker died March 20, 2020, and we will all miss the excitement he expressed at seeing his father’s legacy continue. Current UAB Pathology faculty who received the Roger Denio Baker Prize include Shi Wei, M.D., Ph.D., Professor, and Associate Director, Anatomic Pathology, and Brandi McCleskey, M.D., Assistant Professor, Forensic Pathology. UAB Pathology Celebrates Trainees on Thank a Resident Day
By: Hannah Buckelew
Published Date: Mar 01
Trainees in the UAB Department of Pathology deserve recognition each and every day for their hard work and dedication, but especially on Thank a Resident Day. Last Friday, February 26, the department worked to celebrate trainees by delivering pastries, goodies, and encouraging words. Several UAB Pathology faculty members sent in videos of appreciation for the department's trainees which were shared via the UAB Pathology Instagram account. Read moreUAB Pathology at USCAP 2021
By: Christina Crowe
Published Date: Mar 01
Diversity Dialogue: SOM Hispanic/LATINX Faculty Association
By: Christina Crowe
Published Date: Mar 01
In the summer of 2020, the UAB School of Medicine (SOM) created the Hispanic/LATINX Faculty Association under the leadership of Selwyn Vickers, M.D., Senior Vice President for Medicine, Dean of the School of Medicine and the Office of Diversity and Inclusion (ODI) lead by Mona Fouad, M.D., M.P.H., Professor and Senior Associate Dean. They asked three faculty members to co-lead it: Marcela Frazier from Ophthalmology, Marisa Marques, M.D., from Pathology and Fernando Ovalle from Medicine. The group was initially called simply LATINX, which according to Oxford Languages means “a person of Latin American origin or descent (used as a gender-neutral or nonbinary alternative to Latino or Latina)”, when used as a noun, or “relating to people of Latin American origin or descent (used as a gender-neutral or nonbinary alternative to Latino or Latina)” as an adjective. According to Google, it was introduced less than 20 years ago, which may explain many (perhaps most) faculty members were not familiar with it. For this reason, a permanent name is under debate to encompass individuals either born in Mexico, Central or South America, or Southern Europe (Spain, Portugal, Italy or France) or who have ancestors that came to the United States from one of these countries. Read moreShi Wei, M.D., Ph.D., and Rana Aldrees, M.D., Elected to Alpha Omega Alpha Honor Society
By: Christina Crowe
Published Date: Mar 01
Shi Wei, M.D., Ph.D., Professor, Anatomic Pathology, and Senior Scientist, Experimental Therapeutics, O'Neal Comprehensive Cancer Center, and Rana Aldrees, M.D., PGY4, have been elected to the Alpha Omega Alpha Honor Medical Society (AΩA) at University of Alabama at Birmingham School of Medicine. Wei and Aldrees were chosen from among his peers based on his high academic achievement and his demonstration of leadership, professionalism, research, teaching, and service. Read more |