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Department of Pathology Heersink School of Medicine

Case of the Week

Details

Case History

A 51-year-old female presented with extensive microcalcification in the left breast. The morphology of the partial mastectomy is shown in the figures. ER was positive in 50% of the lesional cells.

Huang_COTW_1_2024.jpg  Huang_COTW_2_2024.jpg

What is the diagnosis?

A. Apocrine ductal carcinoma in situ
B. Apocrine metaplasia
C. Cystic hypersecretory intraductal carcinoma
D. Secretory carcinoma

Correct Answer: C. Cystic hypersecretory intraductal carcinoma

Case contributed by: Xiao Huang, M.D., Ph.D., Assistant Professor, Anatomic Pathology, UAB Pathology