Jeff Hansen
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The inhibitor blocks Streptococcus mutans from sticking on the tooth surface. About 2.3 billion people worldwide have tooth decay in their permanent teeth, primarily caused by this bacteria.
The August issue of the journal focused on genomics in rheumatic diseases, the complex effort to understand the genetic underpinnings of more than 100 diseases that affect joints and muscles.
Pozzo-Miller works on brain penetrant drug research to improve brain performance in Rett syndrome mice.
This potential chemotherapeutic agent to treat glioblastoma — a primary brain tumor with dismal survival rates — is a novel small molecule inhibitor.
This novel method improves purification of complex proteins by 10- to 500-fold, and it may aid both research and large-scale industrial production.
This active drug-delivery system addresses the limitations seen for the anti-cancer drug BA-TPQ — poor solubility and low bioavailability.
The goal is to avoid unnecessary surgery and reduce the number of biopsies of benign nodules and cancers that are unlikely to cause harm.
This is the first demonstration of donor microbes persisting in the recipient following fecal transplant, a finding made possible by a novel method to “fingerprint” individual strains of bacteria.
Allostery, a fundamental means of regulating enzymes, is crucial for living cells.
A biomarker, endothelial mitochondrial function, may be useful for early identification of newborn babies at risk for lung disease and could enable novel therapy approaches.