A230902

Mentor: Dr. Ming He, Department of Pathology

Description 

A postdoctoral position is immediately available for a highly motivated candidate to work on an NIH funded translational project in the laboratories of Dr. Ming He (Department of Pathology).

The project focuses on the epigenetic regulations (e.g., RNA editing and histone modifications) in vascular smooth muscle cells and endothelial cells under hyperglycemia, shear stress, aging, or other cardiovascular risk factors. Our research interest is to synergize basic mechanistic research and clinical evidence to elucidate epigenomic and epitranscriptomic regulations in vascular cells, including the identification of new pathophysiological mechanisms and therapeutic targets for human cardiovascular diseases. The complete List of PI’s published work in MyBibliography: https://www.ncbi.nlm.nih.gov/myncbi/1vWQwz5t9RvAD/bibliography/public/

The successful applicant will be able to generate hypotheses, design experiments, interpret data, troubleshoot, and accurately document experiments. They must be able to analyze and interpret data from different sources and draw relevant conclusions, present results at internal and external meetings, and contribute to the writing of reports and manuscripts. Required skills include tissue culture, experimental mouse husbandry, expression analysis, immunoprecipitation-Western blots, gene knock-down approaches, immunohistochemistry, RNA preparation, gene cloning, and PCR.

The initial appointment will be for one year with the possibility of extension contingent on satisfactory performance. Salary will follow NIH guidelines commensurate with training and experience. 

Qualifications 

Postdoc candidates should have Ph.D., M.D., or an equivalent degree. Previous research experience in vascular diseases/physiology, or biochemistry/molecular/cell biology, or bioinformatics, or related areas is preferred. 

 
Interested candidates should submit CV, a cover letter detailing research experience and contact details of three references to: 
 
Dr. Ming He, Ph.D. & M.D. 
Division of Molecular and Cellular Pathology, 
Department of Pathology 
University of Alabama at Birmingham (UAB). 
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.  

What we offer?

A dynamic and stimulating working environment in a young, enthusiastic, motivated international team with English as main language.

• You will be offered excellent training, leaning state-of-the-art technologies in biomedical research.
• You will receive an annual travel allowance to conferences, e.g., AHA Scientific Sessions or Vascular Discovery – ATVB meeting.

• The UAB has multiple core facilities managed by a team of experts, all the members in PI’s lab have the access to core facilities.
• Training in project management (e.g. supervision of master students, writing of manuscripts and funding proposal, budget management) which will give you the opportunity to develop your career path, your competences and your skills.
• The unique opportunity to work in a multidisciplinary international team and to contribute to the discovery and development of novel therapeutic targets.
• Starting as soon as possible.