June 30, 2010
BIRMINGHAM, Ala. - There may be an obesity epidemic in America, but researchers at the University of Alabama at Birmingham (UAB) are wondering if a few extra pounds on grandma and grandpa are a bad thing. The CrossRoads trial, a collaboration between the Department of Nutrition Sciences and the Division of Gerontology, Geriatrics and Palliative Care, will examine the effect of physical activity and diet on body composition in older adults and any changes that makes on the quality of life for seniors.
"Weight loss for the sake of weight loss might not be appropriate for older adults," said Jamy Ard, M.D., associate professor of nutrition sciences and a study co-investigator. "We really don't understand all of the potential risks or potential benefits of weight loss in seniors."
"Studies have shown that overweight seniors tend to live longer than their leaner counterparts, and we know that rapid weight loss in older adults can lead to a decline in overall physical condition," said Julie Locher, Ph.D., associate professor of gerontology, geriatrics and palliative care and a study co-investigator.
Locher says that the percentage of body fat - particularly abdominal fat that is associated with poor health outcomes - tends to increase with age. But, she says, when older adults lose weight they also have a greater tendency to lose lean muscle mass.
A new question has to be answered, said Locher. "What is a healthy weight for seniors, and how can we devise strategies to help them maximize and maintain lean muscle and minimize abdominal fat?"
The CrossRoads trial will enroll 180 older adults, and they will be divided into three groups. One group will be asked to simply increase their physical activity. A second will increase physical activity and switch to a healthier diet. The third will increase physical activity, eat a healthier diet and also reduce their calorie intake.
"We're going to look at changes in body composition among the three groups during the course of one year," said Ard. "We'll be measuring the percentage of body fat and track the participants overall health, physical condition, wellness and quality of life."
"Our hypothesis is that the second group, who exercise and eat right without losing much weight, will tend to score higher than the other two groups," said Locher. "We hope to gain some valuable insights on the role of weight, body composition and healthy lifestyle behaviors in older adults."
CrossRoads is recruiting adults age 65 and older in general good health who also are taking medication for high blood pressure or diabetes. Participants should be at least 50 lbs overweight with a body mass index between 30-40 kg/m2.
Participants will attend nutritional classes and supervised exercise sessions during the year. Compensation and incentives are provided. Those interested in learning more about the trial can call 205-996-5295.
About the Department of Nutrition Sciences
The Department of Nutrition Sciences is a leader in nutritional research, patient care and education that consistently ranks among the top programs of its kind in the country. Progressive clinics supported by the department average 2,500 patients a year in programs for nutrition, weight management, osteoporosis prevention and cancer support.
About the Division of Gerontology, Geriatrics and Palliative Care
The Division of Gerontology, Geriatrics, and Palliative Care serves older adults and patients with advanced or life-threatening illness by providing leadership and core faculty for innovative models of clinical care; teaching and instructing students, fellows and residents; and conducting research that generates new knowledge contributing to the advancement of science and the quality of life.