A team of UAB researchers including microbiology department assistant professor Beatriz León, Ph.D., and her husband, Andre Ballesteros-Tato, Ph.D., (Clinical Immunology and Rheumatology) have identified a previously unknown step in the pathway that leads to asthma. The results of their study are published online, ahead of print, in “T follicular helper cell plasticity shapes pathogenic T helper 2 cell-mediated immunity to inhaled house dust mite.” A team of UAB researchers including microbiology department assistant professor Beatriz León, Ph.D., and her husband, Andre Ballesteros-Tato, Ph.D., (Clinical Immunology and Rheumatology) have identified a previously unknown step in the pathway that leads to asthma. The results of their study are published online, ahead of print, in “T follicular helper cell plasticity shapes pathogenic T helper 2 cell-mediated immunity to inhaled house dust mite.”“This finding really changes the way we might think about treating allergic diseases and also has important implications when thinking about how young children are first exposed and sensitized to allergens,” said Frances Lund, Ph.D., professor and chair of the microbiology department and a co-author.
Read more